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| STUDENT BIOGRAPHY |
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| Jie Zhou |
| Graduate Student |
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| I grew up in Yangzhou, China. Yangzhou, where Marco Polo once served as a municipal official, is a city with a history of 2500 years, and has once been one of the wealthiest cities in the world. However, now it is such a peaceful city that you can hardly imagine its glorious past. After living in Yangzhou for 18 years, I went to University of Science and Technology of China and got a B.S. degree in Biological Science.
My undergraduate work is mainly about cell cycle regulation in human cells. I was trying to answer a simple and interesting question: How cells determine the exact time for anaphase separation and what happen if the clock is perturbed? Taking advantage of data obtained in Cancer Genome Project (CGP), I first examined the cellular effect of mutations of mitotic regulators found in CGP. Then I narrowed down my experiment hot-spot to Aurora kinases, and sought to find how cancer-related mutations affect their functions and downstream pathways, and finally lead to changes in microtubule plasticity and chromosome segregation.
I am interested in cell dynamics and plasticity, and Columbia University is an ideal place for me to explore different topics in the field. Besides science, I am interested in reading, cooking, traveling, visiting museums, tasting different food, and listening to light music.
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